Beasley, Allen, Crow, Methvin, Portis & Miles, P.C.

William T. Creasman was listed as the author of an article written by a freelance writer for the December 1998 Journal of Women’s Health. The title: “Is there an association between hormone replacement therapy and breast cancer?” The article points out that there is no “definitive evidence” that HRT is linked to breast cancer. But the dirty little secret behind that article in the medical journal is that Creasman didn’t actually write the article. It was authored by a writer for DesignWrite, a marketing firm that represented HRT-maker Wyeth, now owned by Pfizer. As the story was going to press, Wyeth was covering up evidence that proved otherwise. The drug company’s estrogen-plus-progestin HRT was, in fact, increasing a woman’s risk for breast cancer as well as heart disease and Alzheimer’s.

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The advertisements no longer blanket magazines or fill television screens, but the message cannot be deleted. Over the years, millions of women were told that estrogen loss during menopause could be dangerous to their health, contributing to problems such as osteoporosis, heart disease, colon cancer, Alzheimer’s disease, tooth loss and blindness. It could also cause uncomfortable symptoms such as hot flashes, vaginal dryness and mood swings. The ads said menopause was a nasty disease that could be eliminated by just taking a once-daily pill, a hormone replacement therapy (HRT) that would help women feel like women again.

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The message was heard loud and clear – powerful drug companies that make billions from products they know pose a significant risk of life-threatening health consequences to the people who take them, owe their victims. Big time.

This week, Pfizer, which recently acquired Wyeth, the makers of the hormone replacement therapies (HRT) Prempro and Premarin, were hit with more than $100 million in two punitive-damage awards from Philadelphia juries. The two plaintiffs, Connie Barton and Donna Kendall, claimed the drugs caused their breast cancer.

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Drug maker Wyeth paid ghostwriters to write articles for medical journals that were favorable to the company’s hormone replacement therapy (HRT) Prempro , even after the drug was found to raise a woman’s risk for breast cancer and other serious health concerns, according to newly unveiled court documents. Medical journals such as The American Journal of Obstetrics and Gynecology and The International Journal of Cardiology name doctors as authors of articles that typically involve heavily research topics and offer a judgment on how to treat a particular condition. It is believed that doctors are often swayed by those published opinions and may be influenced by them when prescribing medication to their patients.

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Researchers in Ottawa, Canada are hoping to ease women’s fear of hormone replacement drugs by creating and testing synthetic hormones to combat aggravating symptoms of menopause, according to Canada.com. The research follows an earlier grant from the Canadian Breast Cancer Foundation to explore the re-engineering of estrogen estradiol, which is one of the components of the popular hormone replacement therapy (HRT) Premarin. The new grant, funded by a $267,000 research grant from the Canadian Breast Cancer Foundation, seeks to evaluate those compounds of synthesized molecules on the liver, cardiac and other types of cells. The goal is that it must relieve menopausal symptoms while not promoting breast or uterine cancer.

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In the 1960s, a New York gynecologist wrote a book called “Feminine Forever,” in which he recommended estrogen for menopause, stating that women on the hormone replacement drug “will be much more pleasant to live with and will not become dull and unattractive.”

Wyeth Pharmaceuticals caught wind of the book and its author’s claims that estrogen reduced a woman’s risk for both breast and genital cancers, and began distributing the book to physicians across the country. Soon after, sales of Wyeth’s HRT drug Premarin took off, growing to more than 30 million prescriptions each year.

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Nevada’s attorney general is suing drug makers Wyeth and Pfizer for alleged deceptive trade practices and misleading the public about the safety of its hormone replacement therapy (HRT) drugs, according to RGJ.com.

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Wyeth Pharmaceuticals recently announced FDA approval of its Premarin Vaginal Cream to treat moderate to severe dyspareunia, or painful sexual intercourse, according to RTT News.

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Wyeth, the pharmaceutical company that makes hormone replacement therapies Prempro and Premarin, announced today that it is ending its research in its signature areas of contraceptives and menopause treatments to focus on other female problems such as ovarian and breast cancers, according to the Associated Press/Washington Post.

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Drug maker Wyeth has developed and is actively testing a new drug to treat menopause. The drug, named Aprela, has shown favorable results in the initial studies. Current evidence gathered in the study suggests that the drug may pose fewer risks and milder side effects than Prempro and Premarin, Wyeth’s other menopause drugs.

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