Greater reduction in HRT/breast cancer rates in urban, affluent towns
July 8th, 2009 by Jennifer Walker-Journey
A decrease in reported cases of breast cancer across the country linked to the decline of hormone replacement therapy (HRT) is more significant in affluent, urban areas, according to a study published in the journal BMC Medicine.
The study, conducted by researchers at Northern California Cancer Center in Fremont, tracked overall incidence of invasive breast cancer from 2001 to 2004, and noted that the rate of breast cancer fell by 13.8 percent in urban areas but by only 7.5 percent in rural areas. Neighborhoods in high-income areas also reported 13 percent fewer incidence of breast cancer compared to a 9.6 percent decline in poor counties.
Breast cancer reports in rural counties peaked in 1999 and then steadily declined while breast cancer reports in urban counties didn’t reflect significant decline until after 2002. In 2002, the Women’s Health Initiative abruptly halted its trail on postmenopausal women and HRT after data indicated women on HRT were at greater risk for serious health concerns, in particular breast cancer.
Authors of the Cancer Center study say that the pattern of decline in the rate of breast cancer in rural versus urban counties is “consistent with the changing pattern of (HRT) prevalence and cessation or noninitiation.”
The study also indicated that breast cancer was most likely diagnosed in urban areas versus suburban or rural communities. While HRT appears to be the primary cause, the authors caution that some changes could be explained by “saturation or decreases in mammographic screening.”
Source: MedPage Today
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